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Yi-Chang Liu Selected Research

heteronemin

1/2021A Marine Terpenoid, Heteronemin, Induces Both the Apoptosis and Ferroptosis of Hepatocellular Carcinoma Cells and Involves the ROS and MAPK Pathways.
12/2018Heteronemin Induces Anti-Proliferation in Cholangiocarcinoma Cells via Inhibiting TGF-β Pathway.
6/2018Breaking down Leukemia Walls: Heteronemin, a Sesterterpene Derivative, Induces Apoptosis in Leukemia Molt4 Cells through Oxidative Stress, Mitochondrial Dysfunction and Induction of Talin Expression.
6/2018Heteronemin, a Marine Sesterterpenoid-Type Metabolite, Induces Apoptosis in Prostate LNcap Cells via Oxidative and ER Stress Combined with the Inhibition of Topoisomerase II and Hsp90.

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Yi-Chang Liu Research Topics

Disease

15Neoplasms (Cancer)
06/2022 - 05/2004
9Infections
04/2022 - 12/2008
8Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2021 - 11/2003
6Leukemia
05/2022 - 05/2006
6BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
05/2022 - 11/2003
4Carcinogenesis
06/2022 - 08/2006
4Lymphoma (Lymphomas)
06/2022 - 03/2015
4Disease Progression
01/2020 - 10/2013
4Multiple Myeloma
01/2019 - 06/2014
3Prostatic Neoplasms (Prostate Cancer)
05/2022 - 06/2018
3Myelodysplastic Syndromes (Myelodysplastic Syndrome)
12/2021 - 11/2003
3Squamous Cell Carcinoma of Head and Neck
02/2021 - 07/2014
3Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2019 - 01/2015
3Neoplasm Metastasis (Metastasis)
12/2018 - 12/2005
3Blast Crisis (Blast Phase)
12/2014 - 04/2011
2Hematologic Neoplasms (Hematological Malignancy)
10/2022 - 11/2017
2Cytomegalovirus Infections (Inclusion Disease)
04/2022 - 04/2012
2Hepatitis
10/2021 - 01/2019
2Hepatitis B
10/2021 - 01/2019
2Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
09/2021 - 01/2017
2Mouth Neoplasms (Oral Cancer)
09/2021 - 07/2020
2Cholangiocarcinoma
01/2021 - 12/2018
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
11/2017 - 11/2003
2Herpes Zoster
09/2015 - 12/2008
2Lymphoproliferative Disorders (Lymphoproliferative Disorder)
10/2014 - 12/2006
2Thrombosis (Thrombus)
11/2007 - 11/2007
1Pneumonia (Pneumonitis)
11/2022
1Aspergillosis
10/2022
1Chronic Disease (Chronic Diseases)
10/2022
1Stomach Neoplasms (Stomach Cancer)
06/2022
1Thrombocytopenia (Thrombopenia)
05/2022
1Anemia
05/2022
1Leukopenia
05/2022
1Philadelphia Chromosome
05/2022
1Invasive Fungal Infections
04/2022
1Interstitial Cystitis (Interstitial Cystitis, Chronic)
12/2021
1Extranodal Extension
02/2021
1Hypopharyngeal Neoplasms
02/2021
1Hepatocellular Carcinoma (Hepatoma)
01/2021
1Hypersensitivity (Allergy)
01/2021
1Neuroendocrine Carcinoma
01/2020
1Hepatic Veno-Occlusive Disease (Disease, Hepatic Veno-Occlusive)
03/2019
1Breast Neoplasms (Breast Cancer)
02/2019

Drug/Important Bio-Agent (IBA)

5Imatinib Mesylate (Gleevec)FDA Link
12/2014 - 12/2006
4Biomarkers (Surrogate Marker)IBA
06/2022 - 12/2014
4heteroneminIBA
01/2021 - 06/2018
3Matrix Metalloproteinases (MMPs)IBA
07/2020 - 10/2016
3Rituximab (Mabthera)FDA Link
01/2019 - 09/2015
2Pharmaceutical PreparationsIBA
05/2022 - 06/2018
2Antiviral Agents (Antivirals)IBA
10/2021 - 01/2019
2Hepatitis B Surface Antigens (HBsAg)FDA Link
10/2021 - 01/2019
2AnthracyclinesIBA
09/2021 - 01/2017
2DNA (Deoxyribonucleic Acid)IBA
02/2017 - 12/2006
2Fluorouracil (Carac)FDA LinkGeneric
07/2014 - 05/2004
2Cisplatin (Platino)FDA LinkGeneric
07/2014 - 06/2013
2Lipocalin-2IBA
08/2013 - 06/2013
2Hemoglobins (Hemoglobin)IBA
01/2013 - 11/2007
2Janus Kinase 2IBA
03/2011 - 11/2007
1SteroidsIBA
10/2022
1galactomannanIBA
10/2022
1Estrogen Receptor alphaIBA
06/2022
1Leucine (L-Leucine)FDA Link
06/2022
1aeroplysinin IIBA
05/2022
1AlkaloidsIBA
05/2022
1nilotinibFDA Link
05/2022
1Serum AlbuminIBA
09/2021
1TegafurIBA
02/2021
1UracilIBA
02/2021
1Biological ProductsIBA
01/2021
1Cytarabine (Cytosar-U)FDA LinkGeneric
01/2021
1Arginine (L-Arginine)FDA Link
01/2021
1manoalideIBA
01/2021
1Terpenes (Terpenoids)IBA
01/2021
1Argininosuccinate Synthase (Argininosuccinate Synthetase)IBA
01/2021
1Type I DNA Topoisomerases (Topoisomerase I)IBA
01/2021
1ADI PEG20IBA
01/2021
1Small Interfering RNA (siRNA)IBA
07/2020
113-acetoxysarcocrassolideIBA
07/2020
1Reactive Oxygen Species (Oxygen Radicals)IBA
07/2020
1PlatinumIBA
01/2020
1TLC 388IBA
01/2020
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
04/2019
1TensinsIBA
04/2019
1thymoglobulinFDA Link
03/2019
1Ethanol (Ethyl Alcohol)IBA
02/2019
1RNA (Ribonucleic Acid)IBA
12/2018
1Transforming Growth Factors (Transforming Growth Factor)IBA
12/2018
1Transcription Factors (Transcription Factor)IBA
12/2018
1Smad Proteins (Mothers Against Decapentaplegic Homolog)IBA
12/2018
1Messenger RNA (mRNA)IBA
12/2018
1Proteins (Proteins, Gene)FDA Link
12/2018

Therapy/Procedure

10Drug Therapy (Chemotherapy)
02/2021 - 05/2004
9Therapeutics
10/2022 - 05/2006
8Hematopoietic Stem Cell Transplantation
11/2022 - 06/2010
3Transplantation
04/2022 - 01/2019
2Chemoradiotherapy
02/2021 - 07/2014
2Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)
12/2003 - 11/2003
1Adjuvant Chemoradiotherapy
02/2021
1Immunotherapy
01/2019
1Stem Cell Transplantation
01/2019